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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157527Generated: November 2, 2026

Potassium Cation → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(2-hydroxyethyl)-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/157527

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
Reactant2-Methyl-2-butanolHCID 6405—
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
ReactantDibenzylidene acetoneHCID 95417—
Reactant2-Chloro-6-(2-hydroxyethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-oneHCID 58216646—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(2-hydroxyethyl)-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl]amino}thiophene-3-carboxamideHCID 44554108—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-994b3313b6ec4f4b99f7355b11b092bf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)