Dichloromethane → tert-Butyl 3-((((benzyloxy)carbonyl)amino)methyl)-4-hydroxypyrrolidine-1-carboxylate

HRID 1575338Notes

Reaction equation

HRID 1575338 reaction equation
[CH2:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[O:23][C:24](=[O:25])[O:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][C:32]1=[O:33].[Cl:34][CH2:35][Cl:36].[NH2:1][CH2:2][CH:3]1[CH2:4][N:5]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:6][CH:7]1[OH:8]>>[NH:1]([CH2:2][CH:3]1[CH2:4][N:5]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:6][CH:7]1[OH:8])[C:24]([O:23][CH2:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)=[O:25]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 83172Benzyl succinimido carbonateHCID 10584835Tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate

Product 1

HCID 57415726tert-Butyl 3-((((benzyloxy)carbonyl)amino)methyl)-4-hydroxypyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-b400f0d606914a0dad36bb4334a5c37e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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