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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1575352Generated: November 1, 2026

Diethyl Ether → Methyl 2-(2,4-difluorophenylamino)-5-fluoro-6-(2,4,6-trimethylbenzenesulfonyloxy)nicotinate

https://huagongshe.com/reaction/1575352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant2-Mesitylenesulfonyl chlorideHCID 13046—
ReactantMethyl 2-(2,4-difluorophenylamino)-5-fluoro-6-hydroxynicotinateHCID 178498343—
ProductMethyl 2-(2,4-difluorophenylamino)-5-fluoro-6-(2,4,6-trimethylbenzenesulfonyloxy)nicotinateHCID 13821758—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-e96eaf2cb1844746b34a609815a6d60d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)