Piperidine-1-sulfonyl chloride → N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-1-piperidinesulfonamide

HRID 1575783Notes

Reaction equation

HRID 1575783 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:19]3[c:20]([F:26])[c:21]([NH2:22])[cH:23][cH:24][cH:25]3)[n:10][c:11]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[s:12]2)[n:7]1.[N:27]1([S:33](=[O:34])(=[O:35])[Cl:36])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:19]3[c:20]([F:26])[c:21]([NH:22][S:33]([N:27]4[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]4)(=[O:34])=[O:35])[cH:23][cH:24][cH:25]3)[n:10][c:11]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[s:12]2)[n:7]1

Participants

3

Reactant 2

HCID 11298344Piperidine-1-sulfonyl chlorideHCID 579897213-(5-(2-Chloropyrimidin-4-yl)-2-morpholinothiazol-4-yl)-2-fluoroaniline

Product 1

HCID 57989828N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-1-piperidinesulfonamide

Sources & evidence

ORD record
ord-8d5436b387e84cd0beab0021289f7e68
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…