Water → HCID 53680142, compound

HRID 1576027Notes

Reaction equation

HRID 1576027 reaction equation
[C:1]1([CH:7]2[NH:11][N:10]=[C:9]3[C:12](=[CH:18][C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[CH2:13][S:14](=[O:17])(=[O:16])[CH2:15][CH:8]23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.[C:26](OC(=O)C)(=[O:28])[CH3:27]>C(O)(=O)C>[C:26]([N:11]1[CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:8]2[CH2:15][S:14](=[O:16])(=[O:17])[CH2:13][C:12](=[CH:18][C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[C:9]2=[N:10]1)(=[O:28])[CH3:27]

Participants

5

Reactant 3

HCID 962WaterHCID 7918Acetic AnhydrideHCID 68137094HCID 68137094, compound

Product 1

HCID 53680142HCID 53680142, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A suspension of 1.6g of 2,3,3a,4,6,7-hexahydro-3-phenyl-7-(phenylmethylene)thiopyrano[4,3-c]pyrazole-5,5-dioxide in 2ml of acetic anhydride and 30ml of acetic acid is heated on a steam bath for 15 minutes. Hot water (50ml) is added with stirring and the solution is allowed to cool to room temperature. The solids are collected and washed well with water and dried in vacuo over phosphorus pentoxide at 50°C to yield 1.65g of the title compound, melting point 218°-219.5°C.

Workup

  1. temperatureis heated on a steam bath for 15 minutes
  2. customThe solids are collected
  3. washwashed well with water
  4. dry with materialdried in vacuo over phosphorus pentoxide at 50°C

Sources & evidence

ORD record
ord-10ae9d98dfc942beb7d50e0ef8961580
Source dataset
uspto-grants-1976_09
Patent number
US03979381

Reaction notes

Loading…