Sulfuryl chloride → HCID 21514375, compound

HRID 1576100Notes

Reaction equation

HRID 1576100 reaction equation
[C:1]1([C:7]([NH:9][C:10]2[NH:11][CH:12]=[CH:13][N:14]=2)=[S:8])C=C[CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:18])(=O)=[O:16]>C(Cl)(Cl)Cl>[ClH:18].[O:16]1[CH:4]=[CH:3][CH:2]=[C:1]1[C:7]1[S:8][N:11]2[CH:12]=[CH:13][N:14]=[C:10]2[N:9]=1

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 54451730HCID 54451730, compound

Product 1

HCID 21514375HCID 21514375, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

To a solution of 0.19 g. of 2-(2-furylthiocarbonylamino)-imidazole [(IV), R = 2-furyl] in 25 ml. of chloroform, at 20°-25°C, there is added dropwise 0.09 ml. of sulfuryl chloride in 5 ml. of chloroform. After four hours, the reaction mixture is chilled in ice, followed by filtration to yield 2-(2-furyl)-1,2,4-thiadiazolo-[2,3-a]-imidazole hydrochloride.

Workup

  1. temperaturethe reaction mixture is chilled in ice
  2. filtrationfollowed by filtration

Sources & evidence

ORD record
ord-0be89c68d2ad45ed960a0fb3636405ee
Source dataset
uspto-grants-1976_09
Patent number
US03979404

Reaction notes

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