Sodium Hydroxide → HCID 13126154, compound

HRID 1576106Notes

Reaction equation

HRID 1576106 reaction equation
CO[CH:3]1[CH2:7][CH2:6][CH:5](OC)O1.Br.[NH:11]([C:13]1[NH:14][CH2:15][CH2:16][N:17]=1)[NH2:12].[OH-].[Na+]>>[N:12]1([NH:11][C:13]2[NH:17][CH2:16][CH2:15][N:14]=2)[CH:3]=[CH:7][CH:6]=[CH:5]1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 790982,5-DimethoxytetrahydrofuranHCID 30850992-Hydrazino-delta-2-imidazoline hydrobromide

Product 1

HCID 13126154HCID 13126154, compound

Procedure

By reacting 3.7 g. (0.0280 mole) of 2,5-dimethoxy-tetrahydrofuran with 5 g. (0.0276 mole) of 2-hydrazino-4,5-dihydro-1H-imidazole hydrobromide according to the process reported in Example 3, and adding at the end of the reaction a 10% aqueous solution of sodium hydroxide, the title compound is obtained as the free base. Yield 1.5 g. M.p. 183°-4°C. (from acetone.) The maleate melts at 142°-5°C (from acetone).

Sources & evidence

ORD record
ord-7aff89c00c804c3db5a98acc735b3b46
Source dataset
uspto-grants-1976_09
Patent number
US03979408

Reaction notes

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