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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1576148Generated: November 2, 2026

Cyclohexanone → Morpholine, 4-(1-cyclohexen-1-yl)-

https://huagongshe.com/reaction/1576148

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanoneHCID 7967—
ReactantMorpholineHCID 8083—
SolventTolueneHCID 1140—
ProductMorpholine, 4-(1-cyclohexen-1-yl)-HCID 6958994%

Reaction Steps

Illustratively, cyclohexanone may be reacted with morpholine by refluxing these reactants in toluene for a period of about three hours at a temperature of about 110° Centigrade (°C) to yield the preferred enamine reactant, 1-morpholino-1-cyclohexene, in a yield of about 94 percent together with water which is readily removed therefrom.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03979455
Source datasetuspto-grants-1976_09
ORD IDord-1305d88021f54518ba48e7a86a20a92b
Source noteuspto-grants-1976_09