Sodium Carbonate → HCID 86733965, compound

Participants

Reaction Steps

4,10-Dihydroxy-1',10-dimethyl-9,10-dihydroanthracene-9-spiro-4'-piperidine (5 mg.) in hydrochloric acid (1 ml., 3N) is warmed on the steam bath for 10 minutes. The reaction mixture is basified with sodium carbonate and extracted with ether. The ether extract is washed with brine and evaporated to give a gum which on crystallisation from ethanol gives 4-hydroxy-1'-methyl-10-methylene-9,10-dihydroanthracene-9-spiro-4'-piperidine, m.p. 117°-120°C.

Provenance & Evidence