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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15763Generated: October 26, 2026

Hydrazine hydrate (1:1) → cis-5-(4-Chlorophenylsulfonyl)-4,6-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine

https://huagongshe.com/reaction/15763

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantDimethylformamide dimethyl acetalHCID 78373—
Reactantcis-1-(4-Chlorophenylsulfonyl)-2,6-dimethylpiperidin-4-oneHCID 59342367—
Reactant1-(4-Chlorophenylsulfonyl)-2-(pyrimidin-5-yl)piperidin-4-oneHCID 59342391—
Productcis-5-(4-Chlorophenylsulfonyl)-4,6-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridineHCID 68502247—

Reaction Steps

cis-1-(4-Chlorophenylsulfonyl)-2,6-dimethylpiperidin-4-one (92) was treated with DMF-DMA followed by hydrazine hydrate as described for compound 71 in Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732609B2
Source datasetuspto-grants-2010_06
ORD IDord-1e83bddc5d5d45a3a394b31a1ddd21f9
Source noteuspto-grants-2010_06