9-Acetoxyxanthene → HCID 21512586, compound

HRID 1576388Notes

Reaction equation

HRID 1576388 reaction equation
C(O[CH:5]1[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[O:12][C:11]2[C:6]1=[CH:7][CH:8]=[CH:9][CH:10]=2)(=O)C.[CH3:19][N:20]([CH3:27])[CH:21]1[CH2:26][CH2:25][CH2:24][NH:23][CH2:22]1>C1C=CC=CC=1>[CH:7]1[C:6]2[CH:5]([N:23]3[CH2:24][CH2:25][CH2:26][CH:21]([N:20]([CH3:27])[CH3:19])[CH2:22]3)[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[O:12][C:11]=2[CH:10]=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 125434549-AcetoxyxantheneHCID 144598543-(Dimethylamino)piperidine

Product 1

HCID 21512586HCID 21512586, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 9.92 g. (41.3 mmoles) of 9-acetoxyxanthene and 5.9 g. (46.1 mmoles) of 3-dimethylaminopiperidine in 200 ml. of benzene was refluxed for 18 hours. The mixture was then washed with aqueous sodium bicarbonate solution, dried, and evaporated. Chromatography on alumina (chloroform eluant) afforded 1-(9-xanthenyl)-3-dimethylaminopiperidine, as a colorless oil.

Workup

  1. washThe mixture was then washed with aqueous sodium bicarbonate solution
  2. customdried
  3. customevaporated

Sources & evidence

ORD record
ord-35d005b9417348778630423234bfcdfe
Source dataset
uspto-grants-1976_09
Patent number
US03980788

Reaction notes

Loading…