HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Piperidylmethyl)-dimethylamine → 1-(9-Xanthenyl)-2-(dimethylaminomethyl)-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Piperidylmethyl)-dimethylamine | HCID 252484 | — |
| Reactant | 9-Acetoxyxanthene | HCID 12543454 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(9-Xanthenyl)-2-(dimethylaminomethyl)-piperidine | HCID 44273789 | — |
Reaction Steps
A solution of 3.5 g. (14.6 mmoles) of 9-acetoxyxanthene and 2.1 g. (14.8 mmoles) of 2-(dimethylaminomethyl)-piperidine in 50 ml. of toluene was refluxed for 40 hours. The mixture was then washed with sodium bicarbonate, dried and evaporated. Recrystallization of the residue from hexane afforded 1-(9-xanthenyl)-2-(dimethylaminomethyl)-piperidine, m.p. 81°-83°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03980788 |
| Source dataset | uspto-grants-1976_09 |
| ORD ID | ord-594fd4c453804d96a73b6ee2f34dea9c |
| Source note | uspto-grants-1976_09 |