N,N-dimethyl-3-(pyridin-3-yl)propan-1-amine → 1-(9-Xanthenyl)-3-[3-(dimethylamino)propyl]piperidine

HRID 1576401Notes

Reaction equation

HRID 1576401 reaction equation
C(O[CH:5]1[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[O:12][C:11]2[C:6]1=[CH:7][CH:8]=[CH:9][CH:10]=2)(=O)C.[CH3:19][N:20]([CH3:30])[CH2:21][CH2:22][CH2:23][CH:24]1[CH2:29][CH2:28][CH2:27][NH:26][CH2:25]1.CN(C)CCCC1C=NC=CC=1>[Ru](=O)=O>[CH:7]1[C:6]2[CH:5]([N:26]3[CH2:27][CH2:28][CH2:29][CH:24]([CH2:23][CH2:22][CH2:21][N:20]([CH3:30])[CH3:19])[CH2:25]3)[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[O:12][C:11]=2[CH:10]=[CH:9][CH:8]=1

Participants

5

Reactant 3

HCID 238309N,N-dimethyl-3-(pyridin-3-yl)propan-1-amineHCID 125434549-AcetoxyxantheneHCID 15057302Dimethyl[3-(piperidin-3-yl)propyl]amine

Product 1

HCID 215125741-(9-Xanthenyl)-3-[3-(dimethylamino)propyl]piperidine

Reagents, catalysts & solvents 1

HCID 82848Ruthenium dioxideCatalyst

Procedure

By the procedure of Example 1, reacting 9-acetoxyxanthene with 3-(3-dimethylaminopropyl)piperidine [prepared by hydrogenating 3-(3-dimethylaminopropyl)pyridine in the presence of ruthenium dioxide by the procedure of Example 12] gives 1-(9-xanthenyl)-3-[3-(dimethylamino)propyl]piperidine.

Sources & evidence

ORD record
ord-7107256773c54988a1f8aec5d14e8d69
Source dataset
uspto-grants-1976_09
Patent number
US03980788

Reaction notes

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