Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Selenious Acid → Potassium Hydroxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Selenious Acid | HCID 1091 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 4-Phenyl-3-Buten-2-one | HCID 15909 | — |
| 반응물 | Dimethyl 3-oxoundecane-1,11-dioate | HCID 14825131 | — |
| 반응물 | 3-Oxoundecane-1,11-dioic acid | HCID 21565262 | — |
| 반응물 | Styrylglyoxal | HCID 54180762 | — |
| 반응물 | 14-Phenyl-9,12-dioxo-11-hydroxytetradec-13-enoic acid | HCID 68135606 | — |
| 생성물 | Potassium Hydroxide | HCID 14797 | — |
| 생성물 | 3-Hydroxy-5-oxo-2-styrylcyclopent-1-eneheptanoic acid | HCID 68135699 | — |
반응 단계
Starting materials suitable for the manufacture of the compounds of this invention are styrylglyoxal, conveniently prepared by the selenous acid oxidation of 4-phenyl-3-buten-2-one, and the dialkyl esters of 3-oxoundecane-1,11 -dioic acid. Dimethyl 3-oxoundecane-1,11-dioate is thus saponified with potassium hydroxide and the resulting dicarboxylic acid is allowed to react with styrylglyoxal, thus affording 14-phenyl-9,12-dioxo-11-hydroxytetradec-13-enoic acid. Cyclization of the latter intermediate in the presence of potassium hydroxide results in the instant 3-hydroxy-5-oxo-2-styrylcyclopent-1-eneheptanoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03980700 |
| 출처 데이터셋 | uspto-grants-1976_09 |
| ORD ID | ord-25a3a44e7b3d4171aa3d27da9bdeca97 |
| 출처 메모 | uspto-grants-1976_09 |