Chlorine → HCID 21512653, compound

HRID 1576427Notes

Reaction equation

HRID 1576427 reaction equation
[C:1]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][C:4]([C:7]2([CH3:13])[CH2:11][C:10](=[O:12])[NH:9][NH:8]2)=[CH:3][CH:2]=1.[Cl:20]Cl>C(O)(=O)C>[Cl:20][C:17]1[CH:16]=[CH:15][C:14]([C:1]2[CH:6]=[CH:5][C:4]([C:7]3([CH3:13])[CH2:11][C:10](=[O:12])[NH:9][NH:8]3)=[CH:3][CH:2]=2)=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 24526ChlorineHCID 21512636HCID 21512636, compound

Product 1

HCID 21512653HCID 21512653, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

25.2 g of 3-(4-biphenylyl)-3-methyl-pyrazolidin-5-one are dissolved in 200 ml of acetic acid, a solution of 7.1 g of chlorine in 200 ml of acetic acid is added dropwise while stirring, and the mixture is stirred for a further hour and evaporated. Working up in the usual manner gives 3-(4'-chloro-4-biphenylyl)-3-methyl-pyrazolidin-5-one, m.p. 214°-215°.

Workup

  1. stirringthe mixture is stirred for a further hour
  2. customevaporated

Sources & evidence

ORD record
ord-42687bbba00c464ba1c2cd0c10a02fe8
Source dataset
uspto-grants-1976_09
Patent number
US03980795

Reaction notes

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