Hydrochloric Acid → HCID 131710450, compound

Participants

Reaction Steps

A solution of 18.4 g of 2,3,4,5,-tetrahydro-1H-1,4-diazepino[1,2-a]indole (m.p. 75°-77°) in 200 ml of acetic acid and 45 ml of 2N hydrochloric acid is hydrogenated, at 60° and normal pressure, with 13 g of 5% of palladium/barium sulphate. The mixture is cooled, filtered and evaporated to give 2,3,4,5,11,11a-hexahydro-1H-1,4-diazepino[1,2-a]indole. Hydrochloride, m.p. 234° (from ethanol).

Provenance & Evidence