HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-one → 6-Methoxynaphthyl-alpha-methylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-one | HCID 75582 | — |
| Reactant | Ethyl 6-methoxynaphthyl-alpha-methylacetate | HCID 10422645 | — |
| Reactant | HCID 178420551 | HCID 178420551 | — |
| Product | 6-Methoxynaphthyl-alpha-methylacetic acid | HCID 90323 | — |
Reaction Steps
Thus, for example, by reacting 6-methoxy-2-tetralone with the triphenylphosphorane derived from ethyl 2-halopropionate, 2,2-(1'-carbethoxyeth-1',1'-ylidene)-6-methoxytetralin is prepared. Dehydrogenation thereof provides ethyl 6-methoxynaphthyl-α-methylacetate which upon hydrolysis affords 6-methoxynaphthyl-α-methylacetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03980699 |
| Source dataset | uspto-grants-1976_09 |
| ORD ID | ord-80d24b151e1b44c9ac930a1a5473d433 |
| Source note | uspto-grants-1976_09 |