Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluenesulfonic acid → 6-Acetoxy-2-naphthyl-alpha-methylacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Desmethylnaproxen | HCID 162920 | — |
| 생성물 | 6-Acetoxy-2-naphthyl-alpha-methylacetic acid | HCID 20335192 | — |
반응 단계
A mixture of 2.2 g. of 6-hydroxy-2-naphthyl-α-methylacetic acid, 50 ml. of acetic anhydride, and 100 mg. of p-toluenesulfonic acid is stirred for four hours at 50°C. The mixture is evaporated, water is added, and the mixture is extracted with diethyl ether which is washed with water to neutrality, dried over sodium sulfate, and evaporated to yield 6-acetoxy-2-naphthyl-α-methylacetic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03980699 |
| 출처 데이터셋 | uspto-grants-1976_09 |
| ORD ID | ord-27ee9e02a6f94e1b8638044b0b648da4 |
| 출처 메모 | uspto-grants-1976_09 |