2-nitromethylenetetrahydro-2H-1,3-thiazine → 2-(5,6-Dihydro-4H-1,3-thiazin-2-yl)-N,N-dimethyl-2-nitroethen-1-amine

Participants

Reaction Steps

8.0 G OF TETRAHYDRO-2-(NITROMETHYLENE)-2H-1,3-thiazine, prepared as described in Example 2 of Ser. No. 554,361, 5.95 g of N,N-dimethylformamide dimethyl acetal and 25 ml of chloroform were mixed and the mixture was refluxed for about 16 hours. The solvent then was evaporated under reduced pressure to leave a dark orange solid. Recrystallization from ethyl acetate and methanol gave (1), as a light orange solid, m.p.: 168.5°-170°.

Provenance & Evidence