Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | D-(-)-Fructose | HCID 5984 | — |
| Reactant | Pentane | HCID 8003 | — |
| Solvent | Water | HCID 962 | — |
| Product | 20880-92-6 | HCID 10244345 | — |
Reaction Steps
A mixture of 200 grams of D-fructose, 2 liters of acetone, 2 liters of pentane and 8 grams of ferric chloride is stirred and heated to reflux temperature. The reaction water is condensed and removed using a Dean-Stark type water separator. After the theoretical amount of water is removed, the mixture is cooled to 0°C., neutralized with 7 grams of sodium hydroxide in 10 milliliters of water and filtered. The filtrate is treated with 10 grams Norite SG, refiltered, and then concentrated to a syrup which is crystallized from ether-pentane to give 164.4 grams of product, m.p. 94°-95°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03981860 |
|---|
| Source dataset | uspto-grants-1976_09 |
|---|
| ORD ID | ord-d1c1518a25a84121af1582eb7cf80e97 |
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| Source note | uspto-grants-1976_09 |
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