化工社化工社 化学情報印刷レポート · 研究参考用
Perchloric Acid → trans-5,6,7,8-Tetrahydro-1,6,7-naphthalenetriol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Perchloric Acid | HCID 24247 | — |
| 反応物 | 1a,2,7,7a-Tetrahydronaphtho[2,3-b]oxiren-3-ol | HCID 12445737 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | trans-5,6,7,8-Tetrahydro-1,6,7-naphthalenetriol | HCID 12445740 | — |
反応手順
and reacting the 5,6,7,8-tetrahydro-6,7-epoxy-1-naphthol in tetrahydrofuran with aqueous perchloric acid at a temperature within the range of from about 0° to about 60°C., to form trans-5,6,7,8-tetrahydro-1,6,7-naphthalenetriol XXV which can be converted to the 2,3-trans-1,2,3,4-tetrahydro-5-[2,3-(epoxy)propoxy]-2,3-naphthalenediol XXVI which in turn can be converted to the 2,3-trans-1,2,3,4-tetrahydro-5-[2-hydroxy-3-(substituted amino)propoxy]-2,3-naphthalenediol XXVII in a manner similar to that described hereinbefore.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03982021 |
| 出典データセット | uspto-grants-1976_09 |
| ORD ID | ord-7b8aacc1ac454b7aa624e1eaa9952620 |
| 出典メモ | uspto-grants-1976_09 |