Methyl iodide → HCID 13428332, compound

HRID 1576764Notes

Reaction equation

HRID 1576764 reaction equation
[CH:1]([N:4]1[C:9](=[O:10])[N:8]=[C:7]([S:11][CH3:12])[NH:6][C:5]1=[O:13])([CH3:3])[CH3:2].[Na].[CH3:15]I>C(#N)C>[CH3:15][N:8]1[C:7]([S:11][CH3:12])=[N:6][C:5](=[O:13])[N:4]([CH:1]([CH3:3])[CH3:2])[C:9]1=[O:10]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 68142954HCID 68142954, compound

Product 1

HCID 13428332HCID 13428332, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Eighty parts of sodium 3-isopropyl-6-methylthio-s-triazine-2,4(1H,3H)-dione and 49 parts of methyl iodide are refluxed overnight in 700 parts of acetonitrile. The solvent is evaporated and the residue dissolved in methylene chloride. The methylene chloride solution is washed with water, dried, and evaporated to afford after recrystallization from 1-chlorobutane: hexane 54 parts of 1-methyl-3-isopropyl-6-methylthio-s-triazine-2,4(1H,3H)-dione, m.p. 74°-77°.

Workup

  1. customThe solvent is evaporated
  2. dissolutionthe residue dissolved in methylene chloride
  3. washThe methylene chloride solution is washed with water
  4. customdried
  5. customevaporated
  6. customto afford
  7. customafter recrystallization from 1-chlorobutane

Sources & evidence

ORD record
ord-88f50ba03c5e44aa91d2f0a44b1e39c3
Source dataset
uspto-grants-1976_09
Patent number
US03983116

Reaction notes

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