Aluminium lithium hydride → HCID 21510058, compound

HRID 1576821Notes

Reaction equation

C([O:3][C:4]([C:6]1[C:7]([O:18][CH2:19][CH3:20])=[C:8]2[C:14]([CH3:15])=[N:13][N:12]([CH2:16][CH3:17])[C:9]2=[N:10][CH:11]=1)=O)C.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:19]([O:18][C:7]1[C:6]([CH2:4][OH:3])=[CH:11][N:10]=[C:9]2[N:12]([CH2:16][CH3:17])[N:13]=[C:14]([CH3:15])[C:8]=12)[CH3:20]

Participants

Reactant 2

HCID 21226445Aluminium lithium hydride

HCID 21823858HCID 21823858, compound

Product 1

HCID 21510058HCID 21510058, compoundYield 82%

Procedure

By treating the 4-ethoxy-1-ethyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester (prepared by combining the procedures of Examples 2b and 3a, m.p. 93°-94°) with lithium aluminium hydride as in Example 3b, 4-ethoxy-1-ethyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-methanol is obtained. Yield 82%, m.p. 85°-86°.

Workup

customprepared

Sources & evidence

ORD record: ord-9114c2ad225c463ab42985d73401e449
Source dataset: uspto-grants-1976_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03983128

Reaction notes

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