Sulfuric Acid → HCID 12426735, compound

Participants

Reaction Steps

Into a 150 ml flask, provided with a reflux condenser, were placed 14.6 g of monosec.butylamine dissolved in 15.5 ml of C2H5OH. Added thereto was 30 g of 2-bromo-pentane. This mass was then boiled to reflux temperature for 10-12 hours and thereafter cooled down and neutralized with dilute H2SO4. The whole was then evaporated to dryness. The residue thus obtained was treated with an excess of a 15% NaOH solution and extracted with 3 successive portions of ethyl ether. The ether extracts were then combined and washed with H2O, dried or anhydrous Na2SO4, filtered and the ether removed by evaporation. The residue was distilled under atmospheric pressure and the fraction was gathered which passed over at 160° - 161°C. 15.75 g of N-sec.butyl,N-sec.amylamine were obtained thereby. The picrate shows a melting point of from 61°-63°C (crystals from petroleum ether). The analysis of the picrate gave: calculated C = 48.58%, found C = 48.22%; calculated H = 6.50%, found H = 6.4%.

Provenance & Evidence