Hydrochloric Acid → HCID 53744866, compound

Participants

Reaction Conditions

Reaction Steps

A solution of methyl 6-(1-heptenyl)-3-hydroxybicyclo[3.1.0]-hexane-2-heptanoate (17 mg.) from Example 25 in 5 ml. of methanol containing 0.5 ml. of 10% aqueous sodium carbonate solution is heated at 55° C. for 2 hours. The resulting mixture is then cooled to 0° C., acidified with hydrochloric acid to pH 2, and extracted with diethyl ether. The diethyl ether solution is washed, dried with anhydrous sodium sulfate, and evaporated to give 6-(1-heptenyl)-3-hydroxybicyclo[3.1.0]hexane-2-heptanoic acid. I.R. 1745 and 1700 cm-1.

Provenance & Evidence