2,6-Dimethylaniline → HCID 21412829, compound

Participants

Reaction Conditions

Reaction Steps

2,6-Dimethylaniline (100 grams), the dihexyl acetal of 2-bromoacetaldehyde (70 grams) and sodium carbonate (32 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The mixture is heated at a temperature of about 150°C for a period of about 30 hours. After this time the reaction mixture is cooled to room temperature and is filtered. The filtrate is then distilled under vacuum to yield the desired product the dihexyl acetal of 2-(2,6-dimethylanilino)acetaldehyde as the residue.

Provenance & Evidence