4-(1-Methylethyl)benzaldehyde oxime → N-Hydroxy-4-(propan-2-yl)benzene-1-carboximidoyl chloride

Participants

Reaction Steps

A solution of 5.4 g of tert-butyl hypochlorite in 25 ml of carbon tetrachloride was added dropwise during 15 minutes into a solution of 6.8 g of 4-isopropylbenzaldoxime (m.p. 61°-63°, prepared in the manner described in Example II) in 50 ml of carbon tetrachloride while the temperature was maintained at 15°-23°. The green mixture was stirred for 15 minutes, then concentrated. The oil was crystallized from hexane to give 6 g of 4-isopropylbenzohydroximoyl chloride.

Provenance & Evidence