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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577021Generated: November 1, 2026

p-Anisoyl chloride → 2-(4-Chlorophenyl)-3-(4-hydroxybenzoyl)benzofuran

https://huagongshe.com/reaction/1577021

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Anisoyl chlorideHCID 7477—
Reactant2-(4-Chlorophenyl)-1-benzofuranHCID 4368312—
ReactantPyridinium chlorideHCID 10176127—
Reactant2-(4-Chlorophenyl)-3-(4-methoxybenzoyl)benzofuranHCID 21435260—
Product2-(4-Chlorophenyl)-3-(4-hydroxybenzoyl)benzofuranHCID 21435269—

Reaction Steps

When 2-(4-chlorophenyl)benzofuran was acylated with p-anisoyl chloride as described in the procedure of Example 1 and the resulting 2-(4-chlorophenyl)-3-(4-methoxybenzoyl)benzofuran was demethylated with pyridine hydrochloride as previously described, 2-(4-chlorophenyl)-3-(4-hydroxybenzoyl)benzofuran was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03983245
Source datasetuspto-grants-1976_09
ORD IDord-58b2c3ecba1c48bba9ceb0143e427104
Source noteuspto-grants-1976_09