反应详情

温度

75 °C

2-(4-Methoxycarbonyl-2-methylphenylimino)imidazolidine (2.0 g from Example 4) is dissolved in 4 N hydrochloric acid (30 ml) and heated at 75° C. for 18 hours. After cooling crystals separate which are filtered (2.2 g). Recrystallization from water gives 2-(4-carboxy-2-methylphenylimino)imidazolidine hydrochloride, m.p. 280°-281° C. (dec.).

1. temperatureAfter cooling crystals
2. customseparate which
3. filtrationare filtered (2.2 g)
4. customRecrystallization from water