HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea → N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea | HCID 20567640 | — |
| Reactant | CH2N2Pb | HCID 22262466 | — |
| Product | N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine | HCID 54105532 | — |
Reaction Steps
Reacting N-(2-pyrazinylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3 and chromatographing gives N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea. Reacting this thiourea with lead cyanamide by the procedure of Example 3 gives N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]guanidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04287198 |
| Source dataset | uspto-grants-1981_09 |
| ORD ID | ord-cd4d5cb2e06c4c54a06c43872f5fdde2 |
| Source note | uspto-grants-1981_09 |