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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577222Generated: November 4, 2026

1,3-Propanediamine → 2-(3-Aminopropylamino)pyrazine

https://huagongshe.com/reaction/1577222

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-PropanediamineHCID 428—
ReactantChloropyrazineHCID 73277—
ReactantSodium ethoxideHCID 2723922—
SolventEthanolHCID 702—
Product2-(3-Aminopropylamino)pyrazineHCID 14397407—

Reaction Steps

Reacting 2-chloropyrazine with 1,3-diaminopropane in ethanol containing sodium ethoxide by the procedure of Example 89 gives 2-(3-aminopropylamino)pyrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04287198
Source datasetuspto-grants-1981_09
ORD IDord-d75afbae0488431ebb633487513827a7
Source noteuspto-grants-1981_09