Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577229Generated: November 3, 2026

Ethylamine → N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine

https://huagongshe.com/reaction/1577229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant2-[(Thiazol-2-yl)methylthio]ethylamineHCID 12923403—
ReactantN-cyano-N'-[2-(2-thiazolylmethyl-thio)ethyl]-S-methylisothioureaHCID 20427996—
ProductN-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidineHCID 54127424—

Reaction Steps

Reaction of N-cyano-N'-[2-(2-thiazolylmethylthio)ethyl]-S-methylisothiourea, prepared from 2-[(2-aminoethyl)thiomethyl]thiazole by the procedure of Example 3(c)(i), with ethylamine by the procedure of Example 4 gives N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04287198
Source datasetuspto-grants-1981_09
ORD IDord-b6217b8966a5469b97da665b260814d6
Source noteuspto-grants-1981_09