Chlorosulfonic acid → HCID 20572065, compound

Participants

Reaction Steps

A mixture of 1.00 gm of 2,4-diamino-6-(benzylmethylamino)pyrimidine-3-oxide, 1.15 grams of chlorosulfonic acid and 2.50 grams of di-isopropylethylamine in 25 mls of chloroform is stirred overnight. The mixture is concentrated in vacuo. The residue is stirred with aqueous sodium bicarbonate, filtered, and washed with ether to give 2,6-diamino-4-(benzylmethylamino)-1-(sulfooxy)-pyrimidinium hydroxide, inner salt.

Provenance & Evidence