HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,4-diazepan-1-yl)(furan-2-yl)methanone → (1,4-Diazepan-1-yl)(oxolan-2-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,4-diazepan-1-yl)(furan-2-yl)methanone | HCID 12694336 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (1,4-Diazepan-1-yl)(oxolan-2-yl)methanone | HCID 13100546 | — |
Reaction Steps
N-[2-Furoyl)homopiperazine (33.0 g.) in 200 ml. of ethanol was hydrogenated over 5% rhodium-on-carbon catalyst at three atmospheres pressure. The catalyst was removed by filtration and the product distilled to give the desired product, B.P. 135° at 1 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04287341 |
| Source dataset | uspto-grants-1981_09 |
| ORD ID | ord-e5523ab9c3474918a87ea1d6a869820d |
| Source note | uspto-grants-1981_09 |