HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577352Generated: November 1, 2026
1-Chloro-2-nitrobenzene → 1-Fluoro-2-nitrobenzene
https://huagongshe.com/reaction/1577352
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Chloro-2-nitrobenzene | HCID 6945 | — |
| Reactant | Potassium Fluoride | HCID 522689 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Product | 1-Fluoro-2-nitrobenzene | HCID 73895 | 41% |
Reaction Steps
Potassium fluoride (69.6 g; 1.2 mole) and benzyltriethylammonium chloride (10.7 g; 0.05 mole) were added to molten 2-chloronitrobenzene (157.5 g; 1.0 mole). After stirring at 140° C. for 28 hours and a similar work-up to Example 1, 2-fluoronitrobenzene was obtained in 41% yield together with 7% recovered 2-chloronitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04287374 |
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| Source dataset | uspto-grants-1981_09 |
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| ORD ID | ord-9eb23bd186f740f7924861d12176e845 |
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| Source note | uspto-grants-1981_09 |
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