HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577356Generated: November 3, 2026
1-Chloro-2-nitrobenzene → 1-Fluoro-2-nitrobenzene
https://huagongshe.com/reaction/1577356
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Chloro-2-nitrobenzene | HCID 6945 | — |
| Reactant | Sulfolane | HCID 31347 | — |
| Reactant | Potassium Fluoride | HCID 522689 | — |
| Product | 1-Fluoro-2-nitrobenzene | HCID 73895 | 16% |
Reaction Steps
A mixture of potassium fluoride (61.5 g; 1.06 mole), 2-chloronitrobenzene (157.5 g; 1.0 mole) and sulpholane (88.8 g; 0.74 mole) was heated to 140° C. for 28 hours. 2-Fluoronitrobenzene was obtained in 16% yield together with 61% recovered 2-chloronitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04287374 |
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| Source dataset | uspto-grants-1981_09 |
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| ORD ID | ord-5676c2808bb84e499f5bdc45371affcc |
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| Source note | uspto-grants-1981_09 |
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