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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577527Generated: October 25, 2026

Dimethylamine → (E)-2-[(Dimethylamino)phenylmethylene]-benzo[b]thiophen-3(2H)-one

https://huagongshe.com/reaction/1577527

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
ReactantPhosphorus pentachlorideHCID 24819—
ReactantMethanone, (3-hydroxybenzo[b]thien-2-yl)phenyl-HCID 4712192—
Product(E)-2-[(Dimethylamino)phenylmethylene]-benzo[b]thiophen-3(2H)-oneHCID 704791817%

Reaction Steps

Prepared as in Example 1 from 2-benzoyl-benzo[b]thiophen-3-ol, phosphorus(V) chloride and 40% aqueous dimethylamine solution with a yield of 7% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04288437
Source datasetuspto-grants-1981_09
ORD IDord-4f8e862692ea491983956b96e1e7e580
Source noteuspto-grants-1981_09