Ammonia → HCID 178425126, compound

HRID 1577541Notes

Reaction equation

HRID 1577541 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[C:5]([C:7]1[S:11][C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[C:8]=1[OH:16])=O.P(Cl)(Cl)(Cl)(Cl)Cl.[NH3:26]>>[NH2:26]/[C:5](/[C:4]1[CH:17]=[CH:18][CH:19]=[C:2]([CH3:1])[CH:3]=1)=[C:7]1\[C:8](=[O:16])[C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[S:11]\1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 24819Phosphorus pentachlorideHCID 136147879HCID 136147879, compound

Product 1

HCID 178425126HCID 178425126, compoundYield 36%

Procedure

Prepared as in Example 1 from 2-(3-methylbenzoyl)-benzo[b]-thiophen-3-ol, phosphorus(V) chloride and concentrated ammonia with a yield of 36% of theory. M.p. 114°-115° C. (ethyl acetate/petroleum ether 1:1)

Sources & evidence

ORD record
ord-22239d3af86a48129ceb901cc15f9e7d
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

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