Ammonia → HCID 178435933, compound

HRID 1577542Notes

Reaction equation

HRID 1577542 reaction equation
[CH2:1]([C:3]1[CH:20]=[CH:19][CH:18]=[CH:17][C:4]=1[C:5]([C:7]1[S:11][C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[C:8]=1[OH:16])=O)[CH3:2].P(Cl)(Cl)(Cl)(Cl)Cl.[NH3:27]>>[NH2:27]/[C:5](/[C:4]1[CH:17]=[CH:18][CH:19]=[CH:20][C:3]=1[CH2:1][CH3:2])=[C:7]1\[C:8](=[O:16])[C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[S:11]\1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 24819Phosphorus pentachlorideHCID 20570765HCID 20570765, compound

Product 1

HCID 178435933HCID 178435933, compoundYield 46%

Procedure

Prepared as in Example 1 from 2-(ethyl-benzoyl)benzo[b]-thiophen-3-ol, phosphorus(V) chloride and concentrated ammonia with a yield of 46% of theory. M.p. 132°-133° C. (ethyl acetate/petroleum ether 1:1).

Sources & evidence

ORD record
ord-5075a201ece9499f9033d69794eac79b
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

Loading…