Ammonia → HCID 178510719, compound

HRID 1577545Notes

Reaction equation

HRID 1577545 reaction equation
[Br:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[C:4]([C:6]1[S:10][C:9]2[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=2[C:7]=1[OH:15])=O.P(Cl)(Cl)(Cl)(Cl)Cl.[NH3:26]>>[NH2:26]/[C:4](/[C:3]1[CH:16]=[CH:17][CH:18]=[CH:19][C:2]=1[Br:1])=[C:6]1\[C:7](=[O:15])[C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[S:10]\1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 24819Phosphorus pentachlorideHCID 20570754HCID 20570754, compound

Product 1

HCID 178510719HCID 178510719, compoundYield 42%

Procedure

Prepared as in Example 1 from 2-(2-bromobenzoyl)-benzo[b]-thiophen-3-ol, phosphorus(V) chloride and concentrated aqueous ammonia with a yield of 42% of theory. M.p. 143°-144° C. (petroleum ether/ethyl acetate 1:1).

Sources & evidence

ORD record
ord-ff9f8775396d49ef837bee7a551e75bd
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

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