2-Octylamine → N-(1-methylheptyl)-4-phenylbutyramide

反応式

[C:1]1([CH2:7][CH2:8][CH2:9][C:10](Cl)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:13][CH:14]([NH2:21])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>>[CH3:13][CH:14]([NH:21][C:10](=[O:11])[CH2:9][CH2:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

参加物

反応物 2

HCID 127352-Octylamine

HCID 117898654-Phenylbutanoyl Chloride

生成物 1

HCID 20494534N-(1-methylheptyl)-4-phenylbutyramide

実験手順

4-Phenylbutyryl chloride was reacted with 1-methylheptylamine to provide N-(1-methylheptyl)-4-phenylbutyramide, which, when reduced by reaction with diborane in tetrahydrofuran, provided N-(1-methylheptyl)-4-phenylbutylamine. The amine so formed was reacted with formic acid and formaldehyde to give N-methyl-N-(1-methylheptyl)-4-phenylbutylamine.

出典と根拠

ORDレコード: ord-b14d285856594f6a9f7817c9ee3589d4
出典データセット: uspto-grants-1981_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04289787

反応ノート

読み込み中…