HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-piperazin-1-yl-quinoline → 5-{4-[2-(3-Bromophenyl)ethyl]-1-piperazinyl}-2-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-piperazin-1-yl-quinoline | HCID 49851901 | — |
| Reactant | 2-Methyl-5-(4-[2-(3-nitrophenyl)ethyl]-1-piperazinyl}quinoline | HCID 49851902 | — |
| Reactant | Benzeneethanol, 3-bromo-, 1-methanesulfonate | HCID 57444273 | — |
| Product | 5-{4-[2-(3-Bromophenyl)ethyl]-1-piperazinyl}-2-methylquinoline | HCID 57478284 | 56% |
Reaction Steps
The title compound was prepared in 56% yield using a similar procedure to description D5 starting from 2-methyl-5-(1-piperazinyl)quinoline (D3) and 2-(3-bromophenyl)ethyl methanesulfonate (D13).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732600B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-5db34a42240e480c884c3e96136bf5ea |
| Source note | uspto-grants-2010_06 |