Propargylamine → 1-Nitro-2-(propynylamino)-2-{2-[(2-pyridyl)methylthio]ethylamino)ethylene

Participants

Reaction Steps

A mixture of the product of Step A (2.0 g; 7.03 mmoles) and propargylamine (3.44 g; 62.5 mmoles) in acetonitrile (30 ml) was stirred and heated to reflux temperature under a positive pressure of nitrogen for 1.5 hours then stirred at ambient temperature for 42 hours. The reaction mixture was filtered and the product collected. Recrystallization from acetonitrile gave the title compound; mp 147°-148°.

Provenance & Evidence