2-((2-Aminoethyl)thiomethyl)pyridine → 1-Nitro-2-(propynylamino)-2-{2-[(2-pyridyl)methylthio]ethylamino)ethylene

HRID 1577911Notes

Reaction equation

HRID 1577911 reaction equation
CS[C:3]([NH:8][CH2:9][C:10]#[CH:11])=[CH:4][N+:5]([O-:7])=[O:6].[N:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:18][S:19][CH2:20][CH2:21][NH2:22]>>[N+:5]([CH:4]=[C:3]([NH:8][C:9]#[C:10][CH3:11])[NH:22][CH2:21][CH2:20][S:19][CH2:18][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][N:12]=1)([O-:7])=[O:6]

Participants

3

Reactant 2

HCID 128894012-((2-Aminoethyl)thiomethyl)pyridineHCID 71401969N-[1-(Methylsulfanyl)-2-nitroethenyl]prop-2-yn-1-amine

Product 1

HCID 705701261-Nitro-2-(propynylamino)-2-{2-[(2-pyridyl)methylthio]ethylamino)ethylene

Procedure

A solution of the product of Step A is treated with about an equimolar amount of 2-[(2-pyridyl)methylthio]ethylamine to produce, after workup, the title product.

Workup

  1. customto produce

Sources & evidence

ORD record
ord-bfcd1f0366974e92b7bfd35372325c85
Source dataset
uspto-grants-1981_09
Patent number
US04289876

Reaction notes

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