Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene

Participants

Role	Name	HCID	Charge
Reactant	Propargylamine	HCID 239041	—
Reactant	2-(3-Chloropyrid-2-ylmethylthio)ethylamine	HCID 12951532	—
Reactant	3,3-Dimethoxyprop-2-enenitrile	HCID 22622700	—
Reactant	1-Cyano-2-methoxy-2-[2-((3-chloro-2-pyridyl)methylthio)ethylamino]ethylene	HCID 70572173	—
Product	1-Cyano-2-(2-propynylamino)-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene	HCID 73683988	—

Reaction Steps

When 2-[(3-chloro-2-pyridyl)methylthio]ethylamine is reacted with 1-cyano-2,2-bis(methoxy)ethylene and the resultant 1-cyano-2-methoxy-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene is reacted with propargylamine according to the general procedure of Example 1 Step B the title compound is produced.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04289876
Source dataset	uspto-grants-1981_09
ORD ID	ord-f21b1572311844c3bc33edc9b18a7240
Source note	uspto-grants-1981_09