HRID1578023

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：c1ccc(-c2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1

HCID24670

Phenyl ether-biphenyl mixture

C24H20O

结构：CCCCCC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

HCID169870

17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione

C27H40O4

PRODUCTS

生成物

结构：CC(=O)C1=CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

HCID101964

Pregna-4,16-diene-3,20-dione

C21H28O2

收率 83%

PROCEDURE

实验过程

One gram of 17α-hexanoyloxy-4pregnene-3,20-dione is heated analogously to Example 1 in "Dowtherm" for 80 minutes to 285° C., worked up, separated, and combined. Recrystallization from ethanol yields 600 mg of 4,16-pregnadiene-3,20-dione (83% of theory), m.p. 185°-190° C.

WORKUP

后处理

customseparated
customRecrystallization from ethanol