Methyl iodide → HCID 178503870, compound

Participants

Reaction Steps

26.3 g (0.1 M) of N-(2,6-dichlorophenyl)-N'-acetylthiourea, 6.4 g (0.06 M) of sodium carbonate, 8 ml (0.123 M) of methyliodide and 200 ml of ethanol are mixed and heated for 4 hours in a water bath at 70°-75°. The ethanol is distilled off. The residue is washed with water and filtered. The sediment, after drying, is boiled with 180 ml of iso-propanol and then is filtered. From the filtrate 15.3 g (55.2% of the theoretical yield) of N-(2,6-dichlorophenyl)-N'-acetyl-S-methylisothiourea with a melting point of 137°-141° are isolated.

Provenance & Evidence