反应详情

A solution of 100 millimols (15.2 g) of camphor in 250 ml of toluene is heated for 1 hour at the boil with 100 mmols (5.4 g) of sodium methylate. After cooling, 100 mmols (17.8 g) of p-butoxybenzaldehyde are introduced and the mixture is heated at the reflux temperature for 4 hours. The reaction mixture is cooled and 50 ml of water are then added; the toluene phase is separated off, washed with water, dried over sodium sulphate and concentrated to dryness. The solid residue is crystallised from aqueous isopropanol. After drying, 12 g of a white powder, which melts at 62°, are collected.

1. temperatureAfter cooling
2. temperaturethe mixture is heated at the reflux temperature for 4 hours
3. temperatureThe reaction mixture is cooled
4. customthe toluene phase is separated off
5. washwashed with water
6. dry with materialdried over sodium sulphate
7. concentrationconcentrated to dryness
8. customThe solid residue is crystallised from aqueous isopropanol
9. customAfter drying
10. custom12 g of a white powder, which melts at 62°, are collected