Ethyl bromopyruvate → HCID 20568841, compound

HRID 1578076Notes

Reaction equation

HRID 1578076 reaction equation
[NH2:1][C:2]1[C:11]([O:12][CH2:13][CH3:14])=[N:10][C:9]2[C:4](=[CH:5][C:6]([Br:16])=[C:7]([Br:15])[CH:8]=2)[N:3]=1.Br[CH2:18][C:19](=[O:25])[C:20]([O:22][CH2:23][CH3:24])=[O:21]>C(COC)OC>[Br-:15].[NH2:1][C:2]1[C:11]([O:12][CH2:13][CH3:14])=[N:10][C:9]2[C:4](=[CH:5][C:6]([Br:16])=[C:7]([Br:15])[CH:8]=2)[N+:3]=1[CH2:18][C:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[O:25]

Participants

4

Reactant 2

HCID 66144Ethyl bromopyruvateHCID 20568843HCID 20568843, compound

Product 1

HCID 20568841HCID 20568841, compoundYield 113%

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

A solution of 0.68 g of the product of Step A in 25 ml of dimethoxyethane and 0.5 g of ethyl bromopyruvate was stirred for 5 days at room temperature and the mixture was filtered to obtain 0.6 g of 2-amino-6,7-dibromo-1-carbethoxycarbonylmethyl-3-ethoxy-quinoxalinium bromide as a white crystalline solid.

Workup

  1. filtrationthe mixture was filtered

Sources & evidence

ORD record
ord-265e5dc14e734909b3299ba145c6a89a
Source dataset
uspto-grants-1981_09
Patent number
US04291033

Reaction notes

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