反应详情

A solution of 1.4 g of N,N-dimethyl-1,3-propanediamine in 10 ml of ethanol is added dropwise to a stirred, cooled mixture of 4.1 g of 7-chloro-3-(3,4-dichlorophenyl)-3,4-dihydro-10-hydroxy-1,9(2H,10H)acridinedione in 100 ml of ethanol. The mixture is stirred at room temperature overnight and evaporated to dryness in vacuo. The residue is recrystallized from ethanol to give 7-chloro-3-(3,4-dichlorophenyl)1-[[3-(dimethylamino)propyl]imino]-1,3,4,10-tetrahydro-10-hydroxy-9(2H)acridinone; mp 208°-210° C.

1. temperaturecooled
2. customevaporated to dryness in vacuo
3. customThe residue is recrystallized from ethanol